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Search Results for " muscle spasticity "

9

Compounds

Cat No. Product Name Synonyms Targets
T8452 Dantrolene Others
Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.
T1092 Zolmitriptan 311C90,BW-311C90 5-HT Receptor
Zolmitriptan (311C90) selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries and 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and...
T11986L Mebeverine acid hydrochloride
Mebeverine acid hydrochloride is an effective, oral compound to act directly on the smooth muscle of the gastrointestinal tract to relieve spasticity symptoms.
T0077 Dantrolene sodium Lapatinib ditosylate monohydrate,Dantrolene sodium salt Others , Calcium Channel
Dantrolene sodium (Lapatinib ditosylate monohydrate) salt is a skeletal muscle relaxant and can interfere with excitation-contraction coupling in the muscle fiber. It is used for the treatment of spasticity and other neu...
T72023 JB002 Myosin
JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM. It holds potential for research applications in muscle spasticity, chronic musculoskeletal pain, and hypertrophic cardiomyopathy.
T67952 JB062 Myosin
JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac muscle myosin, and smooth muscle myosin II, respectively. It se...
T8630 Baclofen hydrochloride 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride GABA Receptor
Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, espe...
T21077 Tolperisone free base Mydeton,Atmosgen free base,Mideton,Menopatol,Besnoline free base,Mydocalm
Tolperisone free base, a centrally acting muscle relaxant, has been used for the symptomatic treatment of spasticity and muscle spasm.
T73439 MPH-220
MPH-220 is a selective, orally active skeletal muscle myosin-2 inhibitor that facilitates muscle relaxation. As an anti-spastic agent, it holds potential for research into spasticity and muscle stiffness.
TargetMol